Hi, I will be describing some of the organic name reactions for you guys to refer. Hope they are useful for you! I am hopeful that I can get some data across on the internet for those who have been searching and failing on the internet to get information on the rare topics related to name reactions and so on. Hope it is useful for you guys!
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Jyot!
Hi, I need to confess, and regret that I have not been able to get all the content typed. Actually the images are taking a bit. I need to draw them so that you guys can use them. I am really sorry guys. I’ll try to make up for it in every way I can. Hope you guys keep reading this blog!
I’ve been very weak in stereochemistry from the very beginning. now I will be trying to make a huge effort in trying to understand this subject. This is my first post in this subject, hope to see thousands more!
Hi, it’s been a while since I’ve been studying chemistry. chemistry has been my love, since the very beginning. Since the past few days in the run of life, I’ve never been able to actually concentrate and study chemistry. So this is my effort to keep myself updated in the field of chemistry. I will be writing every day. This is going to be my personal diary in the field of chemistry. and tried to keep as much records of what I have studied in this extra class. I have always been bad at attending classes. This is my effortto create an environment that I had missed for many days now. are really remember those days when I used to attendthe classes of chemistry in my college. I will surely be writing as much as I can, in keeping you poster on what I’m reading. I cope this blog helps you in the field at your studying currently. This is all I want to say right now! Hope to see you guys soon.
Today, I am going to write on a very basic type of reaction. The reaction is famously called aldol condensation. Most of the chemists of the world would be aware of this reaction and its mechanism. Anyhow, I am getting used to this writing, and would appreciate you people to bear with my new found interest.
Aldol condensation is a very useful reaction in the field of chemistry. It is a “bond forming” reaction and thus has wide applications in the field of synthetic chemistry. Independently discovered by Wurtz and Borodin, it involves a neucleophilic addition of a ketone moiety to an aldehyde molecule. This finally results into the synthesis of a ?-hydroxy ketone. Sometimes the ?-hydroxy ketone loses a molecule of water to give ?,?-unsaturated ketone. This reaction is called aldol condensation.
Aldehydes posessing atleast 1 Hydrogen atom is partially converted to its enolate anion by bases such as hydroxide and alkoxide ions.
Because the pKa’s of the aldehyde and water are similar, the solution contains signifi-
cant quantities of both the aldehyde and its enolate. Moreover, their reactivities are com-
plementary. The aldehyde is capable of undergoing nucleophilic addition to its carbonyl
group, and the enolate is a nucleophile capable of adding to a carbonyl group. And as
shown in Figure 18.4, this is exactly what happens. The product of this step is an alkox-
ide, which abstracts a proton from the solvent (usually water or ethanol) to yield a
[3-hydroxy aidehyde. A compound of this type is known as an aldol because it contains
both an aldehyde function and a hydroxyl group (ald + ol = aldol). The reaction is
called aldol addition.
Hi,
I now this is a very new place for you people. Not many of you have been here. But, well there is always a beginning. This is what I would call the “Big Bang” of this site. We have started this site as our initiative to keep up the hard work we have done on building the older version of jchem.info. We are integrating all the data currently so that we can give you the best of the best. We want chemical information free on the internet, and that is what we are working towards. Any chemist without the right references is as helpless as any other human being. This is our effort to provide each chemist what he needs. We would like you people to actively participate in this site and show us what you know about chemistry, and what you can donate to the world in terms of knowledge. We will be glad if you can share your thoughts and experiences in the field of chemistry. I hope you people benefit from this site. This is my genuine effort to get all the chemists of the world into solving each other’s woes.
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TalkChem.com Admin
