Archive for the ‘Synthetic Chemistry’ Category
METHYLENE IODIDE
METHYLENE IODIDE DISTILLATION
In a 1-litre three-necked flask, fitted with a mechanical stirrer, reflux condenser and a thermometer, place 200 g. of iodoform and half of a sodium arsenite solution, prepared from 54′5 g. of A.R. arsenious oxide, 107 g. of A.R. sodium hydroxide and 520 ml. of water. Start the stirrer and heat the [...]
In: Synthetic Chemistry · Tagged with: DISTILLATION
Chalcone preparation
I was finally able to prepare chalcones with the following recation
I’ll post the reaction details as and when possible. This is a great achievement as I was able to seperate the products using column chromatography. I know it wouldn’t be a great thing, but atleast we are on track to doing something great . [...]
In: Synthetic Chemistry · Tagged with: chalcone synthesis, column chromatography
Successful Dimethylation and Isolation of gallacetophenone dimethyl ether
Hey! Finally was able to isolate the dimethly ether of gallacetophenone. Here is what the TLC looked like
Apparently the reactant (right in the tlc) has converted almost completely to the product. The reaction conditions were as follows :
3.36 gm of gallacetophenone(0.02 moles) and 15.8 gm (0.1 mole) was added in 100 ml acetone and refluxed [...]
In: Synthetic Chemistry
Methylation Reaction – A small test!
Today was a good day! I learned a lot from the research reactions that I have been carrying out. Its really a great learning exprience. Okay, today what I did was methylation of my product that I have synthesized earlier. I have described the product synthesis here. Let me call the reactant “A”. Okay, here [...]
In: Synthetic Chemistry · Tagged with: dimethylation, methyl iodide, methylation, selective methylation
Gallacetophenone Synthesis – Synthesis of Gallacetophenone
Here pyrogallol reacts with Acetic Anhydride in presence of Zinc Chloride (Lewis Acid) and acetic acid as a solvent.
Pyrogallol:
IUPAC Name: benzene-1,2,3-triol
Chemical Formula: C6H6O3
Exact Mass: 126.03
Molecular Weight: 126.11
m/z: 126.03 (100.0%), 127.04 (6.7%)
Elemental Analysis: C, 57.14; H, 4.80; O, 38.06
Boiling Point: 309°C
Melting Point: 131-134 °C
Critical Temp: 792.92 [K]
Critical Pres: 99.8 [Bar]
Critical Vol: 311.5 [cm3/mol]
Gibbs Energy: -342.18 [kJ/mol]
Log [...]
In: Synthetic Chemistry · Tagged with: acylation, gallacetophenone, pyrogallol, zinc chloride, zncl2