Pseudo-saccharin ethers.

Pseudo-saccharin chloride reacts with alcohols to give ethers (0-alkyl derivatives of
saccharin) :

Heat a little pseudo-saccharin chloride with excess of the anhydrous alcohol in a test-tube until hydrogen chloride is no longer evolved. Recrystallise from alcohol or other organic solvent. With the lower primary alcohols, heating at 100° for 10 minutes uffices: for higher alcohols, a temperature of 125° is preferable. Secondary alcohols
require longer heating at 125°. A large excess of alcohol should be used when dentifying the lower alcohols and the excess removed by evaporation ; for the higher alcohols, it is better to employ an excess of pseudo-saccharin chloride and the product washed free from the reagent with dilute aqueous alkali erivatives of selected alcohols